Fairly good - but a few things out of balance.
First - let's take the price of the monitors, speakers, and periphrals away and just talk about the tower itself. I could build a PC that would bench within 5-10% of that machine for half the price. If paying twice as much for small increases doesnt bother you then you might as well stop reading.
However, the situation can be remedied - by either spending less or more your choice.
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$4,000 is alot, so I am only scrutinizing so much because of the type of system being built, where every last piece matters.
Leaving my personal preference against Asus out of it, i'm sure you did your research and found its the best bench motherboard. <--- I assert that I dont have to check this.
Let me just say that you are the only perosn I know who can drop about $3,500 on a tower and not end up with a quad core. congradulations - oh wait, I mean oops.
As already mentioned, you do not have enough RAM. In theory your procesor and videocard could be bottlenecked by your RAM, although only under memory intensive tasks.
You are clearly shooting for the best computer ever - and yet, you are going to use the slower IDE Hard drives? ATA 100 instead of SATA 2? ....and...... bottleneck.
Also, you are going to have SLI glory which will then be displayed onto a monitor with 8ms responce time? Infact you may never notice it, that would be up to your own eyes, but if you want to see the glory that is > 125 FPS you cant do it with this monitor. You may want to get 5ms or 2ms - but at the same time if you wouldnt notice (as most none gamers cant notice anything past 72 ish) then you are doing the right thing by saving money here. btw incase you are wondering... 1 / responce time = Hz which is similar to FPS (kinda).
Ahh yes - and with this 4,000 dollar beast you put it... a $35 burner. Now, I'm sure its a great burner, maybe it will never coaster, it could even have a nice family too, but it seems much like having an 8trac in your porscha. Have you ever looked into Plextor? I will never own anything else untill they go out of busines or I die. I dont use the great features all the time - but when I do, it is worth it.
That is all for the specific nit picking, overall the machine will play well - but you are definately spending too much money for this performance level. For that much money and a little bit more clever shopping - you can have a machine much faster than the one configured above.
And Darth Tater - the reaosn one would have so many HDD is for RAID 5. I have it and I <3 it.