I've noticed features missing, but I can't even think of what they were right now so I guess they're nothing I need to use often. A lot of stuff has been added, and it's still faster than any version of Firefox or IE I've tried recently, even with the improvements they're bragging about in Beta Firefox versions.
If it had a more robust extension system then I'd use it more, but as of right now its lacking in comparison to Firefox. If Adblock Plus came out for Chrome maybe I would switch