The simplest and most direct way to address the issue is to remove all the mods, and install them one at a time and load the game. Each mod in itself may be fine in single-player and multiplayer, but the combination of maybe two or more mods together may create your corruption in single-player. There's really no other fix than this, unless you are a coder legend and are willing to decipher the hundreds or thousands of lines of code for all the mods active at once.