Yeah that's pretty much your last option. It seems that your HDD has been completely taken over.
Reinstall windows/whatever os you use. Reformat your HDD, create a new partition, and install it there.
@2nd post from mine, above: Ah this changes everything. It seems that either your computer cannot load the BIOS or that the BIOS itself is corrupted. Or one of many other problems.
Just to get some general info, please do the following/answer these questions:
1. Unplug your HDD and attempt to start your computer. Please reply stating whether you can reach the BIOS or not.
2. Does your HDD spin up or just sit there dead?
3. Does your monitor a) remain in "sleep" mode or b) fully turn on, but still show nothing.
4. What OS do you use?
5. How long have the issues in general been occurring with your computer?
6. Do you have an installation CD for your OS?
7. Does your computer make any beeping noises at any point? If so, how many, long or short, and at what point of operation?
8. Was your antivirus software updated?
9. If you can get into the BIOS, try to boot from a disc, any disc that is bootable just to see if you are able to.
10. Is there anything else you can think of that could be useful in resolving this? (Error messages, hardware malfunctions, any idea where you got the virus from, etc)
Please answer all that you can.
@rogue "real fun to format a 250gb": lucky you, I have dual 500gb drives that were both affected once. 1TB reformatting = maximum boredom.