Now is either the best time to do comp, or the worst time. It all depends on one thing:
Whether or not you have Sombra on your team, or the enemy team.
If Sombra is on your team, you are basically one player down. No one has had enough time to master her, to the point where she is viable in comp. She is a very technical hero.
If Sombra is on the enemy team, now they are a player down. This will be easy points for you.
With this said, is it worth the gamble to play comp? At the moment, I don't think it is.... I actually had a lot more typed, but it was turning into a huge rant, so I've removed it.