Unless you are using VERY intensive applications, like full video production on Adobe Premiere or Adobe After Effects, or using Maya to build a city, you won't notice a difference from 4gb to 8gb. At least, not with the current vista offerings. In a few years, it's more likely. Now the difference from the ddr2 800, to ddr3 1600 is a few. First, the price point. DDR3 is much more expensive, because it's newer and there are less companies that currently have fab plants making the stuff. DDR3 memory has a higher memory latency, that impacts it performance. The big upside to DDR3 is it has a much higher memory bandwidth, while it uses a lot less power, and puts out less heat. Currently, DDR2 1066 and DDR3 1333, are about even in performance, but I believe soon DDR3 will begin to pull away, especially if they get those CAS latencies down. DDR3 is the future.